Monday, December 26, 2016

Heads-up on Antibiotics, Jan 2017


Source

(Starting January 1, 2017 animal owners) must work with a licensed veterinarian with whom they have an established veterinarian-client-patient relationship (VCPR) in order to receive permission to order and use... a VFD drug (i.e., any oral "veterinarian grade" antibiotics).

The use and distribution of antibiotics in animal agriculture is changing and producers of all sizes need to begin preparing to adapt in the coming year. Focusing on the one-health concept of combating antibiotic resistance, the United States Food and Drug Administration (FDA) is working to ensure the judicious use of humanly medically important antibiotics. Changes include eliminating the growth promotion use of human medically important antibiotics and expanding the list of feed-grade antibiotics classified as Veterinary Feed Directive (VFD) drugs. Historically, a majority of feed-grade antibiotics used in or on animal feeds have been available to producers over-the-counter, without approval from a veterinarian. By Jan. 1, 2017 the FDA will move all human medically important feed-grade antibiotics to the VFD drug process.

It is important to note not all antibiotics will be considered VFD drugs (Figure 1). The use of injectable antibiotics will not be affected. 

The last time I used "veterinarian grade" antibiotics was when Herc decided to kick a raccoon's butt.  Unfortunately, the raccoon was in the bottom of a ditch filled with stagnant water.  The fight was a draw.

After a day, his wounds became large, soft and puffy.  At Belladonna's urging I whacked him with a couple of days of antibiotics from our supply.

I still ended up taking him to the vet.  Bella came home from college for the weekend to check Herc out and was worried about him.  The vet said he was healing just fine.

The two times before that I had used antibiotics on myself.  Mrs ERJ frowns on my experimenting with the kids.

I accept no responsibility for any misuse of the information presented here.

Storage life
For those of you who are tempted to lay in a supply of vet-grade antibiotics, I reproduce this table from HERE. It must be noted that the extended life is under ideal storage conditions.

In general, antibiotics lose potency as they age.  "Old" Tetracycline family antibiotics have the potential for liver damage  as they age due to the nature of the chemicals they decay into.

Product

Length of Original Dating Average Total Years Extended Total Shelf Life Obtained
Doxycycline 100mg tablets 2 years 5 years 7 years
Ciprofloxacin 500mg tablets 3 years 10 years 13 years



    Extension Time (Mos.)
Antibiotic Dosage Form No. Lots Tested Mean Range
Amoxicillin sodium Tablets 21 23 22–23
Ampicillin Capsules 5 49 22–64
Ampicillin sodium Injection-solution 8 57 29–87
Cefazolin sodium Powder 10 82 63–110
Ceftriaxone sodium Powder 4 60 44­–69
Cefoperazone sodium Powder 4 46 25–57
Cefoxitin sodium Powder 10 24 24–55
Cephalexin Capsules 6 57 28–135
Cephaprin sodium Powder 13 74 50–114
Chloroquine HCl Injection-solution 4 64 27–98
Ciprofloxacin Suspension 7 32 25–40
Ciprofloxacin Tablets 242 55 12–142
Clindamycin phosphate Injection-solution 31 44 18–77
Doxycycline hyclate Capsules 13 50 37–66
Doxycycline hyclate Powder 31 27 14–52
Doxycycline hyclate Tablets 169 27 15–91
Erythromycine lactobinate Powder 4 60 38–83
Neomycin and polymyxin B sulfates and bacitracin zinc Ophthalmic ointment 5 28 12–40
Penicillin G Powder 15 49 22–95
Penicillin G benzathine Suspension 4 70 61–84
Penicillin G procaine Powder 7 70 67–72
Primaquine phosphate Tablets 12 55 41–80
Spectinomycin HCl Suspension 8 83 55–109
Sulfacetamide sodium Ophthalmic ointment 4 39 35–44
Sulfadiazine silver Cream 37 57 28–204
Sulfadozine and pyrimethamine Tablets 8 67 34–93
Sulfisoxazole Tablets 4 56 45–68
Tetracycline HCl Capsules 11 50 17–133

2 comments:

  1. Good point on the out of date meds and potential effects...

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